POTENCY OF ENDOPHYTIC FUNGI ISOLATED FROM Muntingia calabura AS ANTIFUNGAL SUBSTANCES AGAINST Candida parapsilosis
نویسندگان
چکیده
Alternative is needed to overcome the problem of dandruff caused by C. parapsilosis. Endophytic fungi isolated from plants are capable synthesizing compounds produce various secondary metabolites. This study aimed obtain most active endophytic fungal isolates, determine class compounds, and antifungal activity (M. calabura) against Fifteen isolates M. calabura were coded FDK1-FDK15. There was a color change in media after 30 days cultivation fungi. FDK4 FDK13 have potential as antifungals. extract had highest inhibition zone diameter 20.00 mm. 20 eluates obtained isolation com-pounds (Thin Layer Chromatography), FDK 131, 1314, 1317, 1320 terpenoid group FDK1316 phenol that inhibiting yeast growth. FDK1317 compound isolate growth parapsilosis with an 12.5
منابع مشابه
A review of phenolic antioxidants isolated from endophytic fungi
Oxidative stress caused by overproduction of free radicals or oxygenated radical species plays a major role in causing many diseases. The findings suggest the use of antioxidants as compounds to control the release of these radicals or directly prevent their formation. Therefore, antioxidants can be used as drugs to reduce or prevent oxidative stress. Herbal medicines are the basis of modern ph...
متن کاملCytotoxic chalcones and flavonoids from the leaves of Muntingia calabura.
Two new dihydrochalcones, 2',4'-dihydroxy-3'-methoxydihydrochalcone, (-)-3'-methoxy-2',4',beta-trihydroxydihydrochalcone, a new flavanone, (2 S)-(-)-5'-hydroxy-7,3',4'-trimethoxyflavanone, and a new flavonol derivative, muntingone, along with sixteen known compounds, were isolated from the leaves of Muntingia calabura. The structures of these new compounds were determined using spectral analyse...
متن کاملMolecular differentiation and antifungal susceptibilities of Candida parapsilosis isolated from patients with bloodstream infections.
The genetic heterogeneity and antifungal susceptibility patterns of Candida parapsilosis isolated from blood cultures of patients were investigated in this study. Randomly amplified polymorphic DNA (RAPD) analysis generated 5 unique profiles from 42 isolates. Based on the major DNA fragments of the RAPD profiles, the isolates were identified as RAPD type P1 (29 isolates), P2 (6 isolates), P3 (4...
متن کاملDistribution, virulence attributes and antifungal susceptibility patterns of Candida parapsilosis complex strains isolated from clinical samples.
It was recently proposed that Candida parapsilosis represents a complex composed of three closely related species, i.e., C. parapsilosis sensu stricto, C. orthopsilosis, and C. metapsilosis. The aim of this study was to describe the distribution of C. parapsilosis complex isolates among clinical samples. We also evaluated antifungal susceptibility profiles, in vitro presence of lipase and secre...
متن کاملCharacterization of Antifungal Natural Products Isolated from Endophytic Fungi of Finger Millet (Eleusine coracana).
Finger millet is an ancient African-Indian crop that is resistant to many pathogens including the fungus, Fusarium graminearum. We previously reported the first isolation of putative fungal endophytes from finger millet and showed that the crude extracts of four strains had anti-Fusarium activity. However, active compounds were isolated from only one strain. The objectives of this study were to...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biovalentia: biological research journal
سال: 2022
ISSN: ['2477-1392']
DOI: https://doi.org/10.24233/biov.8.2.2022.226